Pharmaceuticals

Sterile Solutions
Vial
Ampoules
I. V. Fluids
Aerosols
LVP & SVP Solutions

Biopharmaceuticals

Vaccines
Human Insulin
Serums
Plasma Fractions
Bacteria and cell cultures

Bottom mounted Magnetic mixer with speed variation from 50 to 350 RPM
Flush Bottom Outlet value (Zero Dead Leg)
Sterile Flange Connections for Top dish nozzles to enhance CIP, SIP operations
pH sensing through sanitary knuckle port on vessel shell
Conductivity sensing through sanitary knuckle port on vessel shell
Temperature sensing through sanitary knuckle port on vessel shell
Load Cells for weight measurement
Vessel with CIP / SIP able accessories
PLC-based, with Touch Screen MMI and SCADA Packages
Vessels are designed in accordance with ASME BPE Guidelines

Flush bottom outlet value

Zero dead leg design
Valve diaphragm clamped between valve body and actuator
Both value housing and piping connections are free draining
Reliable for CIP and SIP operations

Capacity: Processing Batch sizes from 5 litres to 30000 litres

Key Benefits

Cost Effective solution for complete range of sterile liquid products
Magnetically powered drive, no seals, no shafts, thereby eliminating possibility of contamination
Low Power Consumption compared to conventional agitation systems
Ability to mix till the last drop
Low Shear Forces (less damage to product)

 

CLEANING IN PLACE (CIP) Module is the process used to ensure that, process reactors, vessels and lines are free of organic and inorganic contaminants:

Pharmaceuticals

Sterile Solutions
Vial
Ampoules
I. V. Fluids
Aerosols
LVP & SVP Solutions

Biopharmaceuticals

Vaccines
Human Insulin
Serums
Plasma Fractions
Bacteria & cell cultures

 

CIP cycles can be subjected to the following process machinery

Fermentors
Blending Vessels
Media / Harvest / Storage / Filtration Vessels
Transfer Lines
Process Equipment

Completely Automated Process Cycles
On line display of process parameters with P & I of Operating Systems
Display of Fault messages
Supervisory access code prevent unauthorized changes
Detergent / Acid / Alkali dosing
On Line pH, Conductivity, TOC Sensing
CIP is designed in accordance with ASME BPE and EHEDG guidelines
PLC-based, with Touch Screen MMI and SCADA Packages

Spray device characteristics

The cleaning liquid turns the spray head by means of a specially positioned nozzle
Rapid repitition impact loosens the dirt and washes it off the tank surface
The cleaning effects is optimum at low pressure in small to medium size tanks
With increasing pressure, the rotation speed gets higher, while due to stronger atomization, the reach of the spray gets lower
Operation at the optimum pressure ensures required cleaning results and avoids wear of the nozzle

Effective Cleaning Criteria Factors include

Cleaning Cycle Time
Cleaning Agent and Temperature
Concentration and Chemistry of the Cleaning Agent within the circuit
Degree of Turbulence of the Cleaning Solution
Characteristics of the surface being cleaned
Spray Device Selection (Static Dynamic)

Key Benefits

Validatable process for Sterilization of process equipment
Lower Facility Operating Costs
Minimal dismantling of equipment and piping
Reduced turnaround time for cleaning
WFI requirement for cleaning reduced significantly
Exposure to hazardous activities or entry into tanks, is eliminated

• Oral Liquids
• Suspensions

Process Operations For:

• Material Handling and Transfer
• Sugar Syrup Preparation
• Sugar Syrup Prefiltration
• Solution Preparation
• Solution Storage
• Platform Structure
• Transfer Panels
• CIP System
• Automation

• Raw Material Storage
• Inverted Sugar Storage
• Liquid Glucose Storage
• Glycerin Storage

Solution Storage

• Storage Vessels
• Bottom Entry Propeller Mixer for vigorous MASS MOVEMENT within the vessel
• Lug Mounted Vessel on Platform with Load cells

Sugar Transfer

• Sugar can be transferred through a vacuum system
• Transfer is directly into the Sugar Dissolution Vessel
• Chances of Contamination due to handling greatly reduced
• Process Vessel rated for Vacuum

Inverted Sugar/Glucose Transfer

• Inverted Sugar can be transferred through a twin/tri lobe pump
• EHEDG/3A approved Twin Lobe pumps used
• Transfer is directly into the Sugar Dissolution Vessel
• Transfer Line for Liquid Glucose Transfer is Electrically Heat traced and
• Insulated to maintain the temperature at 60 deg C for EASE of transfer of liquid glucose

Sugar Syrup Preparation

• Jacketed/Insulated/Cladded Vessel
• Bottom Entry Propeller Mixer for vigorous MASS MOVEMENT within the vessel
• Lug Mounted Vessel on Platform with Load cells

Solution Preparation

• Jacketed/Insulated/Cladded Vessel
• Bottom Entry Propeller Mixer for vigorous MASS MOVEMENT within the vessel
• Bottom Entry High Shear Mixer for vigorous CUTTING ACTION within the vessel
• Lug Mounted Vessel on Platform with Load cells

Solution Filteration

• Zero Hold up filter press
• Vessel with number of horizontal plates
• Plates are unitised with Tie Rods at the centre and the periphery of the stack
• Fluid flow is from outside of the plate stack,through spacing between the plates and then through filter media
• Filter media can be filter sheet or filter cloth

Designed for the Process With long experience at the leading edge of vacuum processing, Adam Fabriwerk has developed a system which addresses the fundamental requirements of the served markets, including.

The principal applications for the system are in the pharmaceutical and premium cosmetics sectors.

Flexible process parameters setting
Variable shear force adjustment
Easy to upgrade to reflect the latest processing trends

Pharmaceuticals

Lotions
Creams
Gels
Ointments
Biotech products

Cosmetics

Cold creams
Emulsions
Lotions
Gels
Mascara make-up
Shampoo
Toothpaste

The easy-to-use Mixer control package can incorporate process parameters storage for simple and fast set-up.

• Heating / cooling and insulated jackets complete with temperature control and safety equipment
• Semi Contra Rotary agitator with open slot scraper design
• Short loop product Re-Circulation for smaller batch sizes
• Hydraulic lifting on manufacturing vessel top dish to facilitate product recovery
• Separate pre-mix vessels for wax and water phase
• Process piping with transfer panel design for automated plants
• Cleaning In Place cycles with validation protocols

Vessel Design

Extensive research & development has produced the best combination of vessel and agitation system, offering high productivity, quality and yield.

• Low relative batch size
• Conical design and proven geometric ratios ensure optimum Product flow
• All surface angled to ensure ease of cleaning
• Reliable for CIP and SIP operations

Integrated Vacuum System

• Fully controllable to permit variation of vacuum levels according to the process phase
• Operators on demand for environmentally friendly and low cost Operation
• Vacuum line can be fully flushed for sanitation purposes
• Reliable for CIP and SIP operations

User Friendly Interface

The easy-to-use Mixer control package can incorporate process parameters storage for simple and fast set-up.

• PLC-based, with Touch Screen MMI and SCADA Packages
• Choice of packages to suit application requirements
• Flexible Configuration

Processing Options

A comprehensive range of additional features can be provided to increase the flexibility of the Mixer. Each option is supplied fully integrated into the control system of the unit with appropriate safety features.

Modular Construction

The design of the Mixer enables users to tailor the installation to their requirements. Units can operate on a standalone basis or as part of an integrated system. The core components of every Mixer are:

• Process vessel with a choice of agitation systems
• Vertically, bottom mounted high shear head
• Internal and external High Shearing
• Vacuum generation and control
• User-friendly interface

High Efficiency High Shear Head

The hearts of the Mixer is the vertically mounted, bottom high shear head, which introduced shear, drives product flow and discharges the completed batch.

• Aseptic construction
• Variable shear force adjustment
• No additional pump required for discharge and cleaning

Capacity

capacity 5 to 10000 kgs

Key Benefits

• Highly efficient processing with significantly reduced batch times and operating costs
• Pre-stored process parameters give high batch-to-batch consistency
• End products are stable, glossy and air-free with a consistent specific weight for improved filling performance downstream
• Flexibility: one machine with the capability to manufacture a wide range of products

Capacity 5 - 30,0000 Ltrs

Description / Specification of 200L Blending Vessel

We are involved in offering a wide range of 200L Blending Vessel to our most valued clients. Our range of these are widely appreciated by our clients which are situated all round the nation. We offer our range of it at most affordable prices.

We introduce ourselves as an eminent trader and supplier of an extensive array of  200L Blending Vessel. Prior to dispatch, our quality controllers run numerous tests on the entire range on various parameters of quality and durability. The offered equipment is manufactured using superior quality components with the aid of sophisticated techniques at the vendors' end. Moreover, our precious clients can purchase it in different technical specifications at reasonable price from us within promised time frame.
Features:

Sturdy design
Highly durable
Application specific design 

 

100L blending vessels for buffer preparation (top view)

500L and 50L automated vessels for oncology products

Description / Specification of 100L Filtration Vessels

We are involved in offering a wide range of 100L Filtration Vessels to our most valued clients. Our range of these are widely appreciated by our clients which are situated all round the nation. We offer our range of it at most affordable prices.

We introduce ourselves as an eminent trader and supplier of an extensive array of  100L Filtration Vessels. Prior to dispatch, our quality controllers run numerous tests on the entire range on various parameters of quality and durability. The offered equipment is manufactured using superior quality components with the aid of sophisticated techniques at the vendors' end. Moreover, our precious clients can purchase it in different technical specifications at reasonable price from us within promised time frame.
Features:

Sturdy design
Highly durable
Application specific design 

 

30L blending vessels for vaccine formulation

Description / Specification of Magnetic Mixer

We are involved in offering a wide range of Magnetic Mixer to our most valued clients. Our range of these are widely appreciated by our clients which are situated all round the nation. We offer our range of it at most affordable prices.

We introduce ourselves as an eminent trader and supplier of an extensive array of  Magnetic Mixer. Prior to dispatch, our quality controllers run numerous tests on the entire range on various parameters of quality and durability. The offered equipment is manufactured using superior quality components with the aid of sophisticated techniques at the vendors' end. Moreover, our precious clients can purchase it in different technical specifications at reasonable price from us within promised time frame.
Features:

Sturdy design
Highly durable
Application specific design 

 

Description / Specification of 50 Kgs Automated Cream Mixer

We are involved in offering a wide range of 50 Kgs Automated Cream Mixer to our most valued clients. Our range of these are widely appreciated by our clients which are situated all round the nation. We offer our range of it at most affordable prices.

We introduce ourselves as an eminent trader and supplier of an extensive array of  50 Kgs Automated Cream Mixer. Prior to dispatch, our quality controllers run numerous tests on the entire range on various parameters of quality and durability. The offered equipment is manufactured using superior quality components with the aid of sophisticated techniques at the vendors' end. Moreover, our precious clients can purchase it in different technical specifications at reasonable price from us within promised time frame.
Features:

Sturdy design
Highly durable
Application specific design